Life Extension AMPK Metabolic Activator, 30 vege tabs

 Life Extension AMPK Metabolic Activator, 30 vege tabs QR Code
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AMPK (adenosine monophosphate-activated protein kinase) is an enzyme found in every cell in your body. Referred to as a “metabolic master switch”, AMPK controls a gamut of metabolic pathways that enable us to extract energy from food, store and distribute that energy safely through the body, and ultimately use that energy for everything.

Substantial evidence indicates that restoring AMPK activity not only increases longevity, but works to fight the symptoms of aging in individual body systems. No matter which organ system or underlying disease is involved, if you trace the pathological process far enough back, you will likely encounter a problem related to insufficient AMPK activity. Age-related decline in AMPK is a major cause of unwanted abdominal fat, which in turn reduces insulin sensitivity, produces systemic inflammation. Inflammation is intimately involved in many disorders of aging, such as metabolic syndrome and cardiovascular disease, diabetes, and cancer.

By increasing AMPK activity, the cells will be activated to stop storing fat and start burning fats for energy, which helps to maintain metabolic health, fight inflammation and its associated diseases, for instance diabetes, cardiovascular diseases, aging and cancers.

With this, we’ve created AMPK Metabolic Activator. It has two powerful ingredients that safely trigger AMPK, which promotes youthful metabolism.

Benefits at a Glance:

  • Revitalizes youthful AMPK levels
  • Encourages your body to burn stored abdominal fat
  • Promotes healthy insulin response, cellular metabolism and longevity

This scientifically validated combination of ActivAMP® (Gynostemma pentaphyllum) and hesperidin helps revitalize youthful AMPK activity levels that can mitigate the physical and molecular effects of increased abdominal fat and its negative impacts to the whole body.

AMPK Promotes Youthful Metabolic Health

Increasing the levels and activity of the AMPK enzyme within your body tells your cells to stop storing fat, and start using it to create ATP — a compound that your body uses for cellular energy. And our new AMPK Metabolic Activator combines the citrus flavonoid hesperidin with ActivAMP® G. pentaphyllum extract, two natural ingredients that safely trigger AMPK.1,2

By reducing body fats, particularly around your abdomen, increased AMPK activity helps to improve insulin sensitivity, cholesterol levels, vascular health, immune health, inflammatory markers.1,3

AMPK is an essential part of a weight loss program. But please note: AMPK activation alone won’t be nearly as effective as when combined with a healthy diet and regular exercise.

Slow Aging With AMPK

AMPK activity declines sharply with age, making us less energetic and gain weight easily, while becoming increasingly vulnerable to cancer and diseases associated with impaired DNA and protein function. Known as a “gerosuppressor”, AMPK promotes longevity in a few ways:

  • Triggers increased production of mitochondria4,5
  • Stimulates production and activation of SIRT1, an enzyme that is increased in laboratory animals with extended life spans6
  • Inhibits the master inflammation regulator called NF-kappaB7
  • Promotes the cellular “housekeeping” function called autophagy, a process that the damaged and aged cells remove themselves and eliminate damaged DNA and proteins that can disrupt cellular functions8

So try AMPK Metabolic Activator today … and take the fight against aging and stubborn abdominal fat to the cellular level!


Award Winning Product
Life Extension’s AMPK Metabolic Activator was the winner in the Weight Loss Category for the 2020 US Natural Choice Awards (NCAs)


This supplement should be taken in conjunction with a healthy diet and regular exercise program. Individual results are not guaranteed and results may vary.


  • Do not purchase if outer seal is broken or damaged.
  • When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.


Product References:

  1. J Clin Endocrinol Metab. 96: E782-92.
  2. Obesity, (Silver Spring), 22: 63-71.
  3. Nutr J. 15:6, 2016.This page location is:
  4. O’Neill HM, Holloway GP, Steinberg GR. AMPK regulation of fatty acid metabolism and mitochondrial biogenesis: implications for obesity. Mol Cell Endocrinol.2013 Feb25;366(2):135-51.52.
  5. Wang L, Brautigan DL. alpha-SNAP inhibits AMPK signaling to reduce mitochondrial biogenesis and dephosphorylates Thr172 in AMPK alpha in vitro. Nat Commun. 2013;4:1559.
  6. Ruderman NB, Xu XJ, Nelson L, Cacicedo JM, Saha AK, Lan F, Ido Y. AMPK and SIRT1: along-standing partnership? Am J Physiol Endocrinol Metab. 2010 Apr; 298(4):E751-60.
  7. Salminen A, Hyttinen JM, Kaarniranta K. AMP-activated protein kinase inhibits NF-kappaBsignaling and inflammation: impact on healthspan and life span. J Mol Med (Berl). 2011Jul;89(7):667-76.
  8. Hardie DG. AMPK and autophagy get connected. EMBO J. 2011 Feb 16;30(4):634-5.

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Tags: life, extension, ampk, activator, vege, caps, anti, aging