Life Extension Acetyl-L-Carnitine 500 mg, 100 vege caps

 Life Extension Acetyl-L-Carnitine 500 mg, 100 vege caps QR Code
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The Acetyl-L-Carnitine form of carnitine is better absorbed from our intestine than L-carnitine and crosses the blood-brain barrier more efficiently. The blood-brain barrier is a protective mechanism that blocks harmful substances from passing through to our brain and central nervous system.

 

L-carnitine plays an important role to move fatty acids into the mitochondria as fuel to produce energy. Mitochondria, the powerhouses found within human cells, produce the energy that vital tissues need to keep us vibrant and healthy. Healthy levels of carnitine support optimum functioning of mitochondria and your body’s energy production. 1

The problem is that as we age, levels of carnitine decline in all our tissues, reducing cellular energy production and metabolic activity.2

Boosting carnitine levels with supplements can help:

  • Maintain cellular metabolic activity by assisting in the intracellular transport of fatty acids from the cell fluid into the mitochondria, where fats are oxidized to generate cellular energy.1
  • Inhibit excess accumulation of cellular debris.3
  • Support a healthy concentration of nitric oxide, which helps endothelial cells relax and maintain blood flow, supporting already-healthy blood pressure.4
  • Maintain healthy body fat composition, which in turn supports healthy insulin response and blood sugar levels already within normal range.5,6
  • Support brain cells’ defenses against age-related memory and cognitive decline.7
  • Benefit energy-intensive body systems such as the nervous system and the cardiovascular system by helping to counteract the age-related increase in oxidative stress and the decrease in mitochondrial efficiency.1, 8-11

 

Acetyl-L-carnitine has been shown to promote peripheral nervous system comfort, support healthy mood, energy and overall well-being. 12-23

Supplement Facts

Serving Size 1 vegetarian capsule

Amount Per Serving

Vitamin C (as ascorbyl palmitate)

14 mg

Acetyl-L-Carnitine (from acetyl-L-carnitine hydrochloride)

500 mg

Other ingredients: vegetable cellulose (capsule), microcrystalline cellulose, silica.

Non-GMO

Dosage and Use
  • Take one (1) capsule two to four times daily, or as recommended by a healthcare practitioner.
  • This product is best utilized when taken on an empty stomach with water or juice in divided doses 45 minutes before breakfast and lunch.
Warnings
  • KEEP OUT OF REACH OF CHILDREN
  • DO NOT EXCEED RECOMMENDED DOSE
  • Do not purchase if outer seal is broken or damaged.
  • When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

References
1. Physiol Rev.1998 Apr;78(2):547-81. 
2. Ann N Y Acad Sci. 2004 Jun;1019:406-11.
3. Trends Cell Biol. 2011 Oct;21(10):569-76. 
4. Zhonghua Yi Xue Za Zhi (Taipei). 2001 May;64(5):259-70. 
5. Am J Physiol Cell Physiol. 2007 Feb;292(2):C670-86.  
6. Proc Natl Acad Sci U S A. 1997 Apr 1;94(7):3064-9.
7. Ann N Y Acad Sci. 1998 Nov 20;854:118-27. 
8. J Lipid Res. 2004 Apr;45(4):729-35. 
9. Metabolism. 1997 Dec;46(12):1454-7.
10 Mech Ageing Dev. 1995 Oct 13;84(2):103-12.
11. Ann N Y Acad Sci. 2002 Apr;959:491-507.
12. Biochim Biophys Acta. 2000 Jun 26;1486(1):1-17.
13. Am J Clin Nutr. 2007 Dec;86(6):1738-44.
14. J Neurosci Res. 2006 Aug 1;84(2):398-408.
15. Acta Diabetol. 2003 Oct;40 Suppl 1:S106-13.
16. Biochim Biophys Acta. 2000 Jun 26;1486(1):1-17.
17. Clin Pharmacokinet. 2012 Sep 1;51(9):553-72. 
18. Exp Physiol. 2008 Oct;93(10):1139-46. 
19. Neurochem Res. 2009 Apr;34(4):755-63.
20. Ann N Y Acad Sci. 2004 Nov;1033:117-31. 
21. Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):1876-81. Erratum in: Proc Natl Acad Sci U S A 2002 May 14;99(10):7184.
22. Neurochem Res. 2003 Sep;28(9):1321-8.
23. Ann N Y Acad Sci. 2004 Nov;1033:108-16..
24. Geriatr Gerontol Int. 2010 Jul;10 Suppl 1:S99-106
25. Neuropharmacology. 2008 Aug;55(2):223-9.
26. Arch Gerontol Geriatr. 2008 Mar-Apr;46(2):181-90
27. Eur J Pharmacol. 2007 Sep 10;570(1-3):97-107.
28. Brain Res. 2005 Nov 9;1061(2):114-7.

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