Maintaining normal levels of homocysteine, a metabolic byproduct, is associated with both cardiovascular and cognitive health. The B vitamin folate helps maintain already healthy homocysteine levels. The RDA for folate for adults is 400 mcg a day. Our formula provides 1,700 mcg of folate in the form of L-Methylfolate.

Help maintain already healthy levels of the health biomarker homocysteine with 1,000 mcg of folate a day.

Optimized Folate Benefits

• Supports both cardiovascular & cognitive health
• Helps maintain already-healthy homocysteine levels
• Delivers 1,700 mcg of the B vitamin folate

Folic acid is the most common form of folate supplements. Once ingested, your body is supposed to convert folic acid, a synthetic version of folate, into 5-methyltetrahydrofolate, or 5-MTHF. But research shows that many people lack sufficient activity of the enzyme that's necessary to convert folic acid to 5-MTHF.^1-3 A more useful approach is to take 5-MTHF directly.^4-6

Folate, homocysteine & cardiovascular health

Folate helps maintain healthy homocysteine levels already within the normal range. By helping to inhibit excess homocysteine, folate supports healthy levels of this important cardiovascular health biomarker.¹

5-MTHF, homocysteine & cognitive health

Since people with elevated homocysteine levels have a greater risk of cognitive decline, getting enough folate is especially crucial for aging individuals attempting to maintain cognitive health.^7,8

Take alone or with B12 for enhanced effect

The RDA for folate for non-pregnant or lactating adults is 400 mcg a day. This formula delvers 1,700 mcg of 5-MTHF folate. If you’re looking for a higher dose, try our High Potency Optimized Folate formula, which delivers 8,500 mcg of 5-MTHF. You can combine either formula with vitamin B12 in the form of methylcobalamin, vitamin B6 in either the pyridoxal 5’-phosphate or pyridoxine hydrochloride form, and/or riboflavin.